Table 2. Cardiovascular telemetry in OGH-TG mice and WT littermates.
Heart rate, bpm
|
Pulse pressure, mmHg
|
Systolic blood pressure, mmHg
|
Diastolic blood pressure, mmHg
|
|||||
---|---|---|---|---|---|---|---|---|
Mice | Dark | Light | Dark | Light | Dark | Light | Dark | Light |
WT | 589 ± 21 | 553 ± 16 | 34.3 ± 1.6 | 32.8 ± 1.3 | 128 ± 7 | 115 ± 6 | 93.7 ± 5.4 | 82.1 ± 4.5 |
OGH-TG | 600 ± 13 | 550 ± 14 | 37.1 ± 1.6 | 34.8 ± 1.9 | 133 ± 2 | 122 ± 2 | 96.2 ± 2.4 | 86.7 ± 2.8 |
Blood-pressure and heart-rate measurements were recorded in unrestrained, conscious 12-week-old male mice via transmitters implanted in the aortic arch (n = 5 WT, n = 7 OGH-TG). Collected data from each animal were condensed to single values for light- and dark-cycle averages of heart rate and diastolic and systolic blood pressure. bpm, beats per minute; 1 mmHg = 133 Pa.