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. Author manuscript; available in PMC: 2018 May 5.
Published in final edited form as: J Org Chem. 2017 Apr 17;82(9):4977–4985. doi: 10.1021/acs.joc.7b00409

Table 2.

Cytotoxicity (IC50, μM) of ipomoeassin F and analogues 1–3 and 5′.a

MDA-MB-231 MCF7
Ipomoeassin F 0.014 0.070
1 17.0 > 25
2 2.1 11.3
3 > 25 > 25
5′ > 10 –b
a

The data were obtained from at least two independent experiments, and the standard errors are within 20%.

b

“–” means “not tested”.