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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Kidney Int. 2017 Apr 7;92(1):101–113. doi: 10.1016/j.kint.2017.02.013

Figure 7.

Figure 7

β2AR agonist reduces cardiac changes in ZDF rats. A–C, G: Protein expression of collagen I and IV, fibronectin, and phosphorylated p65 was analyzed using immunoblot analysis. Representative heart sections stained for CD68 positive macrophages by immunohistochemistry (D, original magnification ×100 and ×400). Scale bar: 200 and 50 μm. E, F, H: Real-time RT-PCR was performed to measure mRNA expression of NOS2, MCP-1, TNF-α, IL-1β, and arginase-1. I: Representative M-mode echocardiograms and quantification of left ventricular ejection fraction and fractional shortening. * p < 0.001, §p < 0.05, ||p < 0.005, and #p < 0.01 vs. vehicle-treated ZF lean, †p < 0.001, ‡p < 0.05, and p < 0.005 vs. vehicle-treated ZDF, n=6–9.