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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Kidney Int. 2017 Feb 24;92(1):114–124. doi: 10.1016/j.kint.2016.12.023

Figure 3. EVs induce a shift in renal macrophage phenotype.

Figure 3

Representative images (X40) of immunofluorescence staining for stenotic kidney M1 [CD68 (red)/inducible nitric oxide synthase (green)] and M2 [CD68/arginase-1 (green)] macrophages (double staining yellow). Quantification of stenotic-kidney M1 and M2 macrophages and M1/M2 ratio. *p<0.05 vs. Lean; †p<0.05 vs. MetS; ‡p<0.05 vs. MetS+RAS.