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A: Interleukin (IL)-10 mRNA expression was enriched in EVs compared to MSCs. B: IL-4 protein expression was enriched in EVs compared to MSCs. IL10KD in MSCs using small-interfering RNA induced a significant decrease in IL-10 mRNA (C) and protein (D) compared to untreated MSCs. E: IL-10 mRNA expression was downregulated in EVs derived from IL10KD MSCs compared to EVs derived from untreated MSCs. *p<0.05 vs. MSCs, #p<0.05 vs. EVs.
