Table 2.
Variables | Low muscle mass by height2 and weakness | Low muscle mass by BW and weakness | Low muscle mass by BSA and weakness | Low muscle mass by BMI and weakness | ||||||||
---|---|---|---|---|---|---|---|---|---|---|---|---|
|
|
|
|
|||||||||
non-sarcopenic (n=618) | sarcopenic (n=25) | P | non-sarcopenic (n=570) | sarcopenic (n=73) | P | non-sarcopenic (n=541) | sarcopenic (n=102) | P | non-sarcopenic (n=553) | sarcopenic (n=90) | P | |
Black (%) | 62.5 | 36.0 | 0.01 | 66.0 | 26.0 | <0.001 | 66.4 | 35.3 | <0.001 | 67.3 | 25.6 | <0.001 |
Male (%) | 57.4 | 84.0 | 0.01 | 58.1 | 61.6 | 0.56 | 56.6 | 68.6 | 0.02 | 58.4 | 58.9 | 0.93 |
Diabetes (%) | 43.5 | 56.0 | 0.22 | 41.9 | 60.3 | 0.003 | 42.0 | 54.9 | 0.02 | 41.4 | 60.0 | 0.001 |
Age (year) | 55.9±14.1 | 75.9±9.9 | <0.001 | 54.3±13.3 | 75.2±9.1 | <0.001 | 53.8±13.4 | 72.2±9.5 | <0.001 | 54.1±13.4 | 72.6±9.9 | <0.001 |
Muscle metric (units vary) | 9.5±1.9 | 7.1±0.7 | <0.001 | 33.7±4.2 | 29.2±2.3 | <0.001 | 14.4±1.8 | 12.4±1.3 | <0.001 | 1.0±0.2 | 0.8±0.1 | <0.001 |
BMI (kg/m2) | 28.4±7.0 | 21.8±2.0 | <0.001 | 28.0±7.0 | 29.5±6.4 | 0.09 | 28.8±7.3 | 25.0±3.7 | <0.001 | 28.1±7.1 | 28.6±6.3 | 0.52 |
Percent fat (%) | 30.0±10.2 | 25.9±10.7 | 0.045 | 29.1±10.4 | 35.6±6.3 | <0.001 | 29.8±10.5 | 30.4±8.9 | 0.56 | 29.2±10.4 | 33.8±8.2 | 0.0001 |
Serum creatinine (g/dl) | 8.5±2.7 | 6.6±2.2 | 0.001 | 8.6±2.7 | 6.6±2.0 | <0.001 | 8.7±2.8 | 7.0±2.1 | <0.001 | 8.7±2.7 | 6.8±2.1 | <0.001 |
Serum albumin (g/dl) | 4.0±0.4 | 3.8±0.3 | 0.03 | 4.0±0.4 | 3.9±0.4 | 0.01 | 4.0±0.3 | 3.9±0.4 | 0.005 | 4.0±0.4 | 4.0±0.3 | 0.31 |
Death during follow-up (%) | 69 (11.2) | <10 (<40.0) | <0.001 | 61 (10.7) | 17 (23.3) | 0.002 | 55 (10.2) | 23 (22.5) | <0.001 | 58 (10.5) | 20 (22.2) | 0.002 |
Death rate (per 100 patient- years) | 5.9 [4.6, 7.4] | 24.7 [12.8, 47.4] | <0.001 | 5.6 [4.4, 7.2] | 13.9 [8.7, 22.4] | 0.001 | 5.3 [4.1, 6.9] | 13.4 [8.9, 20.2] | 0.0001 | 5.5 [4.2, 7.1] | 13.3 [8.6, 20.6] | 0.0004 |
Data are presented as mean ± SD, n (%), and [95% confidence interval]