Table 2.
Risk factors for the development of colorectal cancer in patients with inflammatory bowel disease and recommended surveillance[1-7,9,11,13-15,17,18,24]
High risk | Intermediate risk | Low risk | |
Risk factors | PSC Extensive involvement Moderate-severe active inflammation sustained over time (endoscopic or histological) First-degree relative with CRC at an age of less than 50 Stenosis or dysplasia detected during the previous five years Appearance of IBD at a young age1 If ileo-anal pouch: Dysplasia Previous CRC PSC Type C mucosa in the pouch | Extensive colitis with mild or moderate sustained inflammatory activity (endoscopic or histological) Inflammatory polyps First-degree relative with CRC at an age of above 50 | Other factors different from high and intermediate risk |
Surveillance | Annual | Every three years | Every five years |