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MHP results of thiadiazole derivatives with human c-Met receptor using PLATINUM Server.
| Compound name | Area of lipophilic Match (SLL) |
Area of hydrophilic match (SHH) |
Buried surface area (Sburied) |
Total surface area (Stotal) |
Fraction of matching hydrophobic surface |
|---|---|---|---|---|---|
| 4b | 129.49 | 0.76 | 252.97 | 273.35 | 0.6441 |
| 4e | 145.19 | 1.58 | 282.40 | 302.41 | 0.6510 |
| 4g | 159.55 | 1.96 | 272.72 | 291.37 | 0.7108 |
| 4h | 166.33 | 0.44 | 254.49 | 280.25 | 0.7456 |
