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a pH changes measured after addition of saline to vitreous. b–e pH changes measured after addition of various drugs as indicated to vitreous (diamonds) or to saline (circles). Broken lines (addition to vitreous) or dotted lines (addition to saline) indicate mean values. Significance of differences to initial values was calculated by Dunn’s multiple comparison and indicated by asterisks with *p < 0.05, **p < 0.01, ***p < 0.001 and ****p < 0.0001
