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. Author manuscript; available in PMC: 2017 Jun 26.
Published in final edited form as: J Theor Biol. 2014 Mar 5;352:31–50. doi: 10.1016/j.jtbi.2014.02.027

Table 4.

Model parameters.

Symbol Name Value
a0 Typical cell size 5 μm
ra Cell radius growth rate (default) 0.19 μm/s
rp DNA replication rate 0.44 h-1
rbd DNA damage rate (background) 0.01 h-1
rcd DNA damage rate (copied part in S phase) 0.015 h-1
rbr DNA repair rate (background) 0.3 h-1
rn DNA repair rate (non-homologous end joining) 0.1 h-1
rh DNA repair rate (homologous recombination) 0.4 h-1
ks DNA repair suppress constant 0.1
rCDK1 CDK1 production rate 0.48 h-1
rCDK1i CDK1 inhibition rate 0.045 h-1
rCDK2 CDK2 production rate 0.48 h-1
rCDK2i CDK2 inhibition rate 0.075 h-1
rWEE1 WEE1 production rate 0.48 h-1
rCDK1y CDK1y synthesis rate 2.4 h-1
rCDK2E MF synthesis rate 0.48 h-1
dCDK1y CDK1y degradation rate in G2 phase 1 h-1
ath Threshold for a in G1 phase 0.95×21/2×a0
NthCDK2E Threshold for MF in G1 phase 0.99
NthCDK1y Threshold for CDK1y in G2 phase 0.1
Qth Threshold for Q in M phase 0.02
k Repulsive spring constant 5 [k]
η Linear drag coefficient 1 h·[k]