Table 1.
The expression of arginine-glycine-aspartate (RGD)-binding integrins in squamous cell carcinoma tissues from the head and neck.
| Integrin | SE | SCC | E | S | Ref |
|---|---|---|---|---|---|
| αvβ3 | −/+ | −/+ | ++ | + | [43] |
| αvβ3 | − | [44] | |||
| αvβ3 | + | −/+ | [45] | ||
| αvβ3 | −/+ | +++ | [46] | ||
| αvβ5 | + | ++ | ++ | +++ | [43] |
| αvβ5 | + | +++ | [45] | ||
| αvβ5 | + | ++ | ++ | [44] | |
| αvβ1 | +++ | +++ | [45] | ||
| αvβ6 | − | ++ | n/a | [44] | |
| αvβ6 | ++ | +++ | [45] | ||
| αvβ8 | +++ | +++ | [45] | ||
| αIIbβ3 | |||||
| α5β1 | + | ++ | + | ++ | [43] |
| α5β1 | − | +++ | [47] | ||
| α5β1 | −/+ | ++ | [48] |
Key: SE: squamous epithelium; SCC: squamous cell carcinoma; E: endothelial cells; S: stroma; − negative; −/+ weak; + moderate; ++ strong; +++ very strong; blank not tested.