Figure 4.
Cytotoxic effect of TMZ, DOX and PTX on glioma cells. Inhibitory effect of TMZ increasing doses (5, 50, 100, 200 μM) at 72 h: on NO3 NS (B–E); and on NO3 AC (G–J) growth; untreated NS and AC in (A,F), respectively; few surviving cells of NO3 NS line after 120 h treatment with 200 μM TMZ (K); and proliferation restarting after 30 days from treatment suspension (L). All 100× magnification. Reproduced with permission from Annovazzi et al., International Journal of Oncology; published by Spandidos Publications Ltd., 2015 [110].
