FIG 1.

Sensitivity of the Aptima assay. (A) Aptima s/co levels of HIV-1-infected individuals on ART with detectable viral loads plotted against RNA copies/ml as determined by the Roche COBAS AmpliPrep/COBAS TaqMan HIV-1 test. (B) Dilutions of cultured HIV-1 ranging from 3 to 100 copies per ml were tested in 30 replicate measurements. The means and SDs of the resulting s/co ratios on the Aptima assay are shown. (C) Probit analysis of percentage of 30 replicate measurements as described for panel B that yielded a reactive Aptima result at each dilution.