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. 2017 Jun 23;55(7):2116–2126. doi: 10.1128/JCM.00181-17

TABLE 2.

AST results of the Accelerate Pheno system compared to culture-based ASTa

Antimicrobial agent Accelerate Pheno system AST
Culture-based AST (no.)
No. of AST results No. (%) of category agreements
No. (%) of minor discrepancies No. (%) of major discrepancies No. (%) of very major discrepancies Susceptible Resistant
S R/I Total
SAM 66 31 32 63 (95.5) 0 (0) 3 (8.8) 0 (0) 34 32
TZP 91 78 6 84 (92.3) 0 (0) 7 (8.2) 0 (0) 85 6
FEP 90 73 6/1* 80 (88.9) 7 (7.8) 3 (3.6) 0 (0) 83 6/1*
CRO 85 75 8 83 (97.6) 0 (0) 2 (2.6) 0 (0) 77 8
ETP 85 85 0 85 (100) 0 (0) 0 (0) 0 (0) 85 0
MEM 94 91 2 93 (98.9) 1 (1.1) 0 (0) 0 (0) 91 3
AMK 95 91 2 93 (97.9) 1 (1.1) 0 (0) 1 (33.3) 92 3
GEN 94 84 9 93 (98.9) 0 (0) 1 (1.2) 0 (0) 85 9
TOB 94 82 10 92 (97.9) 1 (1.1) 1 (1.2) 0 (0) 84 10
CIP 94 69 21 90 (95.7) 4 (4.3) 0 (0) 0 (0) 73 21
CST 88 85 0 85 (96.6) 0 (0) 3 (3.4) 0 (0) 88 0
Total 976 844 97 941 (96.4) 14 (1.4) 20 (2.3) 1 (1.0) 876 100
a

The overall category agreement was 96.4%. Minor discrepancies, major discrepancies, and very major discrepancies were detected in 1.4, 2.3, and 1.0%, respectively. *, One strain showed an intermediate result for FEP in the Accelerate Pheno system and culture-based ASTs. AMK, amikacin; SAM, ampicillin-sulbactam; FEP, cefepime; CRO, ceftriaxone; CIP, ciprofloxacin; GEN, gentamicin; MEM, meropenem; TZP, piperacillin-tazobactam; TOB, tobramycin; CST, colistin; ETP, ertapenem. S, susceptible; R/I, resistant/intermediate.