TABLE 3.
AST results of the Accelerate Pheno system compared to culture-based AST for 95 Gram-negative pathogens included in the studya
| Organism | No. of strains | No. of AST results | No result (n) | Category agreement (n) | No. of discrepancies |
Comment(s) (n) | ||
|---|---|---|---|---|---|---|---|---|
| Minor | Major | Very major | ||||||
| E. coli | 56 | 608 | 2 | 594 | 6 | 8 | 0 | Min: FEP (3), CIP (2), AMK (1); Maj: SAM (2), FEP (1), CRO (1), GEN (1), TOB (1), CST (2); no result: FEP (1), MEM (1) |
| Klebsiella spp. | 14 | 148 | 2 | 144 | 2 | 2 | 0 | Min: TOB (1), CIP (1); Maj: SAM (1), CST (1); no result: SAM (1), CIP (1) |
| P. aeruginosa | 9 | 72 | 0 | 65 | 1 | 5 | 1 | Min: MEM (1); Maj: TZP (4), FEP (1); VMJ: AMK (1) |
| Enterobacter spp. | 6 | 59 | 0 | 51 | 4 | 4 | 0 | Min: FEP (3), CIP (1); Maj: TZP (3), FEP (1) |
| S. marcescens | 5 | 45 | 0 | 44 | 0 | 1 | 0 | Maj: CRO (1) |
| Proteus spp. | 2 | 20 | 0 | 20 | 0 | 0 | 0 | |
| Citrobacter spp. | 2 | 20 | 0 | 19 | 1 | 0 | 0 | Min: FEP (1) |
| A. baumannii | 1 | 4 | 3 | 4 | 0 | 0 | 0 | No result: SAM (1), TZP (1), FEP (1) |
| Total | 95 | 976 | 7 | 941 | 14 | 20 | 1 | |
a
AMK, amikacin; SAM, ampicillin-sulbactam; FEP, cefepime; CRO, ceftriaxone; CIP, ciprofloxacin; GEN, gentamicin; MEM, meropenem; TZP, piperacillin-tazobactam; TOB, tobramycin; CST, colistin; ETP, ertapenem. Maj, major discrepancy; Min, minor discrepancy; VMJ, very major discrepancy.