Table 1. Luciferase complementation-based reporters for imaging of kinase activities.
Kinase | Substrate | Peptide sequence | Phospho peptide-binding domain | Reference |
---|---|---|---|---|
AKT | FOXO4/AFX1 | QSRPRSCTWPLPRPEKKK | FHA2 | [9] |
ATM | CHK2 | LETVSTQELYSI | FHA2 | [12] |
EGFR | EPS15 | KPANFSAYPSEEDMIE | SH2 | [2] |
FADD KINASES | FADD | QNRSGAMSPMSWNSDASTSEAS | FHA2 | [3] |
GSK3β/CKIα | β-CATENIN | SYLDSGIHSGATTTAPSLSG | FHA2 | [4] |
c-MET | PYK2 | LSESCSIESDIYAEIPDETLR | SH2 | [10] |
TGFβR | SMAD2 | LTQMGSPSVRCSSMS | FHA2 | [6] |