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. Author manuscript; available in PMC: 2017 Jun 26.
Published in final edited form as: Cell Rep. 2016 Nov 15;17(8):1990–2003. doi: 10.1016/j.celrep.2016.10.071

Figure 4. Schematic Model of the Proposed Role of SRSF10, hnRNP F/H, and hnRNP K in Bcl-x Pre-mRNA Splicing, and How Oxali-platin Reprograms Their Interactions.

Figure 4

Repressor complex representing the major regulatory assembly in normally growing 293 cells. (B) Activating complex proposed to form on a minor fraction of Bcl-x transcripts in normally growing 293 cells or when SRSF10 is overex-pressed. (C) Impact of oxaliplatin on the interaction of regulatory components leading to the activation of the 5′ss of Bcl-xS.