Figure 1.
Formulation and characterization of self-encapsulating PLGA microspheres. A) Schematic illustration of the self-encapsulation of protein Ags into PLGA microspheres. B) SEM images of self-encapsulating PLGA microspheres containing CaHPO4 adjuvant gel as the protein-trapping agent. Microspheres are shown before (left) and after (right) self-encapsulation of OVA and pore healing. Scale bars represent 10 μm. C) Summary of key properties of the self-encapsulating microspheres and percentage cumulative OVA release from the microspheres. Data are shown as mean ± SEM (n = 3).