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. Author manuscript; available in PMC: 2017 Jun 26.
Published in final edited form as: Biomaterials. 2017 Mar 6;128:19–32. doi: 10.1016/j.biomaterials.2017.03.002

Figure 8. Transplantation of (PVPON/TA)-encapsulated islets can restore euglycemia to diabetic mice.

Figure 8

Daily blood glucose readings of streptozotocin-treated NOD.Rag mice before and after islet transplantation in the epididymal fat pad with 500 NOD.scid islets encapsulated in (PVPON/TA) (A). IPGTT assay with non-transplanted diabetic (n=5), euglycemic mice transplanted with encapsulated islets (n=5), and non-diabetic controls (n=5) (B). H&E stain (C) and immunofluorescence for insulin, glucagon, and DAPI (D) of (PVPON/TA)-encapsulated islets in the epididymal fat pad at 10X (C) and 40X (D) magnification. TX – islet transplant. * - islet graft removed.