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. Author manuscript; available in PMC: 2018 May 30.
Published in final edited form as: Circulation. 2017 Feb 21;135(22):2091–2101. doi: 10.1161/CIRCULATIONAHA.116.024436

Figure 2. Forest Plot of Incident Coronary Heart Disease After Statin Therapy by Genetic Risk Group in Statin Primary Prevention Trials.

Figure 2

The multi-variable adjusted hazard ratios of incident coronary heart disease after statin therapy by genetic risk group are presented for three primary prevention trials. Data from JUPITER and ASCOT-LLA were obtained from prior analyses.5 Fixed effects meta-analysis was used to estimate the relative effect of statin therapy on incident coronary heart disease across trials for each genetic risk group (P for difference = 0.05). CI = confidence interval; HR = hazard ratio.