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. Author manuscript; available in PMC: 2018 Jul 1.
Published in final edited form as: Biochim Biophys Acta. 2017 Apr 18;1859(7):1273–1281. doi: 10.1016/j.bbamem.2017.04.016

Fig. 6.

Fig. 6

Contribution of VGSC and VGCC to the OMP change in response to nsPEF of increasing amplitude. Experiments were performed in: (A) standard Tyrode solution; (B) Tyrode solution composed without CaCl2; (C) Tyrode solution with 4 μM tetrodotoxin (TTX); and (D) both without CaCl2 and with 4 μM TTX. Each experiment included six OMP recording trials (193 ms, 450 frames each), with a stimulus of indicated amplitude (kV/cm) applied at 50 ms (arrow). The interval between trials was always 1 min. Shown are the mean traces +/− s.e. (for clarity, error bars are drawn for each 10th datapoint only). Note the inhibition of the early depolarization peak by TTX and somewhat larger depolarization response in the 0 Ca2+ solution. See text for more details.