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Effects of fucoidan on cell viability of HCT116 cells. p53+/+ (A) and p53−/− (B) HCT116 cells were treated with the indicated concentrations of fucoidan for 24 h or 48 h. The cell viability was evaluated by a 3-(4,5-dimethyl-2-thiazolyl)-2,5-diphenyl-2H-tetrazolium bromide (MTT) assay. Data are expressed as the mean standard deviation (±SD) of three independent experiments. Significance was determined by the Student t-test (* p < 0.05 vs. untreated control).
