Production of Chitin from Penaeus vannamei By-Products to Pilot Plant Scale Using a Combination of Enzymatic and Chemical Processes and Subsequent Optimization of the Chemical Production of Chitosan by Response Surface Methodology

. 2017 Jun 16;15(6):180. doi: 10.3390/md15060180

Mean Squares Ratios	the Model Is Acceptable When
F1 = Model/Total error	$F 1 \geq F_{d e n}^{n u m}$
F2 = (Model + Lack of fitting)/Model	$F 2 \leq F_{d e n}^{n u m}$
F3 = Total error/Experimental error	$F 3 \leq F_{d e n}^{n u m}$
F4 = Lack of fitting/Experimental error	$F 4 \leq F_{d e n}^{n u m}$