Skip to main content
. Author manuscript; available in PMC: 2017 Jun 26.
Published in final edited form as: Science. 2017 Feb 3;355(6324):524–527. doi: 10.1126/science.aai8982

Figure 2. Condensin is specifically enriched along juxtaposed DNA.

Figure 2

(A) Hi-C contact maps of strains harboring single parS sites at -59° (BWX3377), -94° (BWX3270), and -117° (BWX3381). To visualize interactions in the terminus region, the genome was oriented with the terminus (ter) at the center of the maps. The position of the parS sites and the extent of DNA juxtaposition are indicated by black and blue dotted lines, respectively. (B) Anti-SMC ChIP-seq was performed on the same samples as in (A). ChIP enrichment (ChIP/Input) was plotted in 1 kb bins. Schematics of the juxtaposed regions are shown. SMC enrichment at the highly transcribed genes outside the juxtaposed regions is probably nonspecific (see Figure S3).