FIG. 8.

σ1s determines the extent and severity of reovirus-induced CNS injury. Representative H&E-stained coronal sections of the cortex, thalamus, and hippocampus are shown for C84-MA (A to C), C93 (D to F), and C84 (G to I) (original magnification, ×400). Tissue injury was quantified by using a previously validated neuropathology grading system (J). Each bar represents the average score from four to nine mice. Error bars indicate standard errors of the means. Statistical comparisons are shown in below the corresponding areas of the graph. NS, not significant.