TABLE 1.
Vaccine strain | Dose | DOC | Plasma virus RNA at DOC | EIAV challenge strain | No. of animals protected/no. tested (%)
|
|
---|---|---|---|---|---|---|
Protection from clinical disease | Protection from infection | |||||
EIAVUKΔS2 | 105 | 6 | 102-104 | PV | 8/8 (100) | 8/8 (100) |
EIAVUKΔS2/DU | 105 | 6 | <102-103 | PV | 7/8 (87.5) | 2/8 (25) |
EIAVPRΔS2 | 105 | 6 | <102 | PV | 6/8 (75%) | 0/8 (0) |
EIAVUKΔS2 | 105 | 2 | 102 | PV | 3/5 (60) | 1/5 (20) |
Control | NA | NA | NA | PV | 0/6 (0) | 0/6 (0) |
DOC, day of challenge.