Table 3.
Surgical Diagnoses by Subtype of Atypia
| No. of Nodules | ||||
|---|---|---|---|---|
| Diagnosis | AUS‐A | AUS‐C | AUS‐C/A | Total |
| GEC‐benign | ||||
| Benign histopathology | ||||
| Adenomatous/hyperplasic nodule | 3 | 2 | 1 | 6 |
| Follicular adenoma | 2 | 0 | 2 | 4 |
| GEC‐suspicious | ||||
| Benign histopathology | ||||
| Adenomatous/hyperplasic nodule | 15 | 8 | 14 | 37 |
| Follicular adenoma | 10 | 3 | 1 | 14 |
| Other | 0 | 2a | 0 | 2 |
| Malignant histopathology | ||||
| Classic variant of papillary thyroid carcinoma | 0 | 2 | 3 | 5 |
| Follicular variant of papillary thyroid carcinoma | 4 | 2 | 8 | 14 |
| Noninvasive follicular neoplasm with papillary‐like nuclear features | 1 | 5 | 9 | 15 |
| Follicular thyroid carcinoma | 1 | 1 | 1 | 3 |
| Total | 36 | 25 | 39 | 100 |
Abbreviations: AUS‐A, atypia of undetermined significance (AUS) with architectural atypia; AUS‐C, with cytologic atypia, AUS‐C/A with cytologic and architectural atypia; FNA, fine‐needle aspiration; GEC, gene expression classifier.
a
These included 1 hyalinizing trabecular tumor and 1 case of thyroid tissue with a giant cell reaction to suture in a patient with AUS‐C who underwent previous thyroid surgery.