FIG. 3.

Intracellular IFN-γ production as a measure of HBV-specific T-cell responses in HBV-monoinfected treated individuals (n = 13). CD4⁺ T-cell responses (a) and CD8⁺ T-cell responses (b) to stimulation with an HBV peptide pool of 1 μg ml⁻¹ for each peptide are shown. A response was considered positive if more the 0.05% of CD4⁺ or CD8⁺ T cells produced IFN-γ. n.d., not done.