Table 1.
Schedule of Enrollment, Interventions, and Assessments for Biopsychosocial Influence on Shoulder Pain Pre-Clinical Trial
| STUDY PERIOD | |||||||||
|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||
| Enrollment | Allocation | Post-allocation | Close-out** | ||||||
|
| |||||||||
| TIME POINT | -7d+ | -3d | 0d | 0d | 1d | 2d | 3d | 4d | 5d+ |
|
| |||||||||
| ENROLLMENT: | |||||||||
|
|
|||||||||
| High risk screen | X | ||||||||
|
|
|||||||||
| Eligibility screen | X | ||||||||
|
|
|||||||||
| Informed consent | X | ||||||||
|
|
|||||||||
| Allocation | X | ||||||||
|
| |||||||||
| INTERVENTIONS: | |||||||||
|
|
|||||||||
| Propranolol | X | X | X | X | |||||
|
|
|||||||||
| Psychological Education | X | X | X | ||||||
|
|
|||||||||
| Placebo | X | X | X | X | |||||
|
|
|||||||||
| General Education | X | X | X | ||||||
|
| |||||||||
| ASSESSMENTS: | |||||||||
|
|
|||||||||
| Demographic | X | ||||||||
|
|
|||||||||
| Pain Intensity and Disability | X | X | X | X | X | X | |||
|
|
|||||||||
| Physical Impairment | X | X | X | X | X | ||||
|
|
|||||||||
| Psychological and Pain Sensitivity | X | X | X | X | X | ||||
|
|
|||||||||
| Inflammatory Markers | X | X | X | X | |||||
|
|
|||||||||
| Global Ratings and Blinding | X | ||||||||
*
Time point units are days (d)
**
Participants continued to be followed after last post-allocation day if they do not meet pain recovery criterion for pain intensity and disability measures only.