Extended Data Table 2.

Association between continuous values of log-transformed fasting plasma concentration of pro-neurotensin (pro-NT) (expressed as per 1 SD increment of log-transformed value) in relation to continuous outcome values of body mass index, waist circumference and HOMA-IR in human subjects (Malmö Diet and Cancer Cardiovascular Cohort, MDC-CC).HOMA-IR = Homeostasis Model Assessment of Insulin Resistance; SD = standard deviation; SE = standard error; pro-NT = pro-neurotensin. Based on linear regression model.

Metabolic trait	β-coefficient ± SE (per SD increment of log-transformed pro-NT)	p-value
Body Mass Index (kg/m2)	0.14 ± 0.06	0.016
Waist circumference (cm)	0.33 ± 0.15	0.026
HOMA-IR (mmol/L*mU/L)	0.13 ± 0.015	<0.001