Table 3. Significantly enriched pathways of Alzheimer’s disease-associated genes.
Pathway ID | Pathway description | Observed gene count | False discovery rate | Matching proteins in your network (labels) |
---|---|---|---|---|
GO.1902003 | regulation of beta-amyloid formation | 5 | 8.86E-08 | ABCA7,APOE,CLU,PICALM,SORL1 |
GO.1902996 | regulation of neurofibrillary tangle assembly | 3 | 2.61E-05 | APOE,CLU,SORL1 |
GO.0002443 | leukocyte mediated immunity | 7 | 6.26E-05 | ACE,BCL3,CLU,CR1,HLA-DRB1,IL6R,INPP5D |
GO.0065005 | protein-lipid complex assembly | 4 | 1.59E-04 | ABCA7,APOC1,APOE,BIN1 |