Table 2.
Initial medication after HTX
| Parameter | No use of amiodarone before HTX (n=412) | Acute use of amiodarone before HTX (n=23) | Chronic use of amiodarone before HTX (n=95) | P-value |
|---|---|---|---|---|
| Cyclosporine A, n (%) | 275 (66.7%) | 12 (52.2%) | 53 (55.8%) | 0.0630 |
| Tacrolimus, n (%) | 137 (33.3%) | 11 (47.8%) | 42 (44.2%) | 0.0630 |
| Azathioprine, n (%) | 215 (52.2%) | 9 (39.1%) | 43 (45.3%) | 0.2598 |
| Mycophenolate mofetil, n (%) | 197 (47.8%) | 14 (60.9%) | 52 (54.7%) | 0.2598 |
| Steroids, n (%) | 412 (100.0%) | 23 (100.0%) | 95 (100.0%) | NA |
| Acetylsalicylic acid, n (%) | 31 (7.5%) | 1 (4.3%) | 9 (9.5%) | 0.6711 |
| Beta blocker, n (%) | 66 (16.0%) | 4 (17.4%) | 9 (9.5%) | 0.2560 |
| Ivabradine, n (%) | 23 (5.6%) | 2 (8.7%) | 5 (5.3%) | 0.8067 |
| Calcium channel blocker, n (%) | 103 (25.0%) | 6 (26.1%) | 20 (21.1%) | 0.7071 |
| Dihydropyridine, n (%) | 43 (10.4%) | 2 (8.7%) | 6 (6.3%) | 0.4650 |
| Non-dihydropyridine, n (%) | 60 (14.6%) | 4 (17.4%) | 14 (14.8%) | 0.9329 |
| ACE inhibitor/sartan, n (%) | 194 (47.1%) | 9 (39.1%) | 37 (38.9%) | 0.2964 |
| Diuretic, n (%) | 412 (100.0%) | 23 (100.0%) | 95 (100.0%) | NA |
| Statin, n (%) | 146 (35.4%) | 7 (30.4%) | 37 (38.9%) | 0.6976 |
| Gastric protection (PPI/H2 blocker), n (%) | 412 (100.0%) | 23 (100.0%) | 95 (100.0%) | NA |
Abbreviations: HTX, heart transplantation; ACE, angiotensin-converting enzyme; PPI, proton pump inhibitor; H2, histamine receptor; NA, not applicable.