Table 2.
Multivariable Logistic Regression Models Examining Associations Between Current CAM Use and Chemotherapy Initiation in BQUAL, by Chemotherapy Indication or Discretionary
| Characteristic | Chemotherapy, Odds Ratio (95% CI) | P Value | ||
|---|---|---|---|---|
| Indicated (n = 306) | P Value | Discretionary (n = 379) | ||
| Dietary Supplement Use (Yes vs No)a | ||||
| Model | ||||
| Unadjusted | 0.22 (0.06–0.58) | .006 | 0.76 (0.47–1.24) | .27 |
| Adjustedb | 0.16 (0.03–0.51) | .006 | 0.66 (0.36–1.21) | .18 |
| Mind-Body Practice Use (Yes vs No)c | ||||
| Model | ||||
| Unadjusted | 1.43 (0.66–3.00) | .35 | 0.73 (0.46–1.15) | .17 |
| Adjustedb | 1.45 (0.57–3.59) | .43 | 0.89 (0.50–1.58) | .69 |
| CAM Index (Every 1-Unit Increase)d | ||||
| Model | ||||
| Unadjusted | 0.71 (0.55–0.91) | .008 | 0.85 (0.72–0.99) | .04 |
| Adjustedb | 0.64 (0.46–0.87) | .005 | 0.83 (0.67–1.01) | .07 |
Abbreviations: BQUAL, Breast Cancer Quality of Care Study; CAM, complementary and alternative medicine; OR, odds ratio.
Dietary supplements include vitamin and/or minerals, herbs and/or botanicals, and other natural products.
Adjusted models controlled for age, race/ethnicity, education, grade, tumor size, estrogen receptor and/or progesterone receptor status, ERBB2 (formerly HER2 or HER2/neu) status, and Charlson comorbidity score.
Mind-body practices include self-practice and practitioner-based therapies.
The CAM index is based on the sum of the score of using each of the following five modalities: vitamins and/or minerals, herbs and/or botanical, other natural products, self-practice mind-body therapies, and practitioner-based mind-body therapies.