Table 1.
Treatment | Urinary output (mL)
|
||||
---|---|---|---|---|---|
1st hour | 2nd hour | 3rd hour | 4th hour | 5th hour | |
Distilled water | 0.39 ± 0.63 | 0.67 ± 0.70 | 0.98 ± 0.93 | 1.04 ± 1.01 | 1.48 ± 0.77 |
Furosemide (10 mg/kg) | 1.85 ± 0.87 | 3.64 ± 1.38* | 5.05 ± 1.13** | 6.48 ± 2.19*** | 7.05 ± 2.28*** |
ACMS (62.5 mg/kg) | 1.46 ± 1.37 | 2.85 ± 1.45 | 4.13 ± 1.19* | 6.60 ± 1.50*** | 7.52 ± 0.99*** |
ACMS (125 mg/kg) | 1.77 ± 1.44 | 2.82 ± 1.47 | 4.00 ± 1.95* | 5.36 ± 1.91** | 6.95 ± 1.90*** |
ACMS (250 mg/kg) | 0.6 ± 0.57 | 2.01 ± 1.04 | 3.68 ± 1.26 | 4.8 ± 0.60* | 5.34 ± 0.45 *** |
ACMS (500 mg/kg) | 0.85 ± 1.49 | 1.92 ± 1.59 | 3.16 ± 2.15 | 4.99 ± 2.25* | 6.01 ± 1.94** |
Notes: Values represent mean ± standard error of mean (n = 6).
P < 0.05;
P < 0.01;
P < 0.001.
Abbreviation: ACMS, aqueous crude extract of M. stenopetala.