Table 5.
Urinary electrolyte excretion after administration of aqueous extract of Moringa stenopetala leaves in rats
| Treatment | Electrolyte excretion (mmol/L)
|
Natriuretic
|
Saliuretic
|
CAI
|
Saliuretic index
|
||||
|---|---|---|---|---|---|---|---|---|---|
| Na+ | K+ | Cl− | Na+/K+ | Na+ + Cl− | Cl−/Na+ + K+ | Na+ | K+ | Cl− | |
| Distilled water | 81.23 ± 5.83 | 52.26 ± 4.02 | 122.24 ± 7.63 | 1.56 | 203.00 | 0.92 | |||
| Furosemide (10 mg/kg) | 200.64 ± 5.34*** | 101.01 ± 3.40*** | 245.55 ± 6.0*** | 1.38 | 451.00 | 0.81 | 2.47 | 1.93 | 2.00 |
| ACMS (62.5 mg/kg) | 137.2 ± 5.44*** | 55.6 ± 2.89 | 154 ± 5.57 | 2.49*** | 0.89 | 0.80 | 1.69 | 1.07 | 1.26 |
| ACMS (125 mg/kg) | 151 ± 6.47*** | 50.4 ± 3.80 | 163.2 ± 10.63** | 3.04*** | 0.93 | 0.81 | 1.86 | 0.97 | 1.34 |
| ACMS (250 mg/kg) | 150.2 ± 4.97*** | 55 ± 3.87 | 173 ± 7.30** | 2.77*** | 0.87 | 0.84 | 1.85 | 1.06 | 1.42 |
| ACMS (500 mg/kg) | 159.6 ± 9.00*** | 77.6 ± 6.65** | 170.6 ± 12.22** | 2.10* | 0.94 | 0.72 | 1.97 | 1.49 | 1.40 |
Notes: Values represent mean ± standard error of mean (n = 6).
*
P < 0.05;
**
P < 0.01;
***
P < 0.001.
Abbreviations: CAI, carbonic anhydrase inhibition; ACMS, aqueous crude extract of M. stenopetala.