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. Author manuscript; available in PMC: 2018 Jan 1.
Published in final edited form as: Lancet Haematol. 2016 Dec 1;4(1):e24–e34. doi: 10.1016/S2352-3026(16)30166-1

Table 2.

Total investigator-assessed response rates by disease characteristics following C1 + RC

TGA (1,000 mg)
n=15
TGB (2,000 mg)
n=22
Total
N=37

All patients, % (n/N) 47 (7/15) 68 (15/22) 59 (23/37)

Prior therapy, % (n/N)

Yes 42 (5/12) 69 (11/16) 57 (16/28)
No 67 (2/3) 67 (4/6) 67 (6/9)

Prior rituximab, % (n/N)

Yes 36 (4/11) 64 (9/14) 52 (13/25)
No 75 (3/4) 75 (6/8) 75 (9/12)

Baseline IgM level, % (n/N)

<4 g/dL 67 (6/9) 63 (10/16) 64 (16/25)
≥4 g/dL 17 (1/6) 83 (5/6) 50 (6/12)

IgM=immunoglobin M. TGA=Treatment Group A. TGB=Treatment Group B.