Table 2.
Total investigator-assessed response rates by disease characteristics following C1 + RC
TGA (1,000 mg) n=15 |
TGB (2,000 mg) n=22 |
Total N=37 |
|
---|---|---|---|
| |||
All patients, % (n/N) | 47 (7/15) | 68 (15/22) | 59 (23/37) |
| |||
Prior therapy, % (n/N) | |||
| |||
Yes | 42 (5/12) | 69 (11/16) | 57 (16/28) |
No | 67 (2/3) | 67 (4/6) | 67 (6/9) |
| |||
Prior rituximab, % (n/N) | |||
| |||
Yes | 36 (4/11) | 64 (9/14) | 52 (13/25) |
No | 75 (3/4) | 75 (6/8) | 75 (9/12) |
| |||
Baseline IgM level, % (n/N) | |||
| |||
<4 g/dL | 67 (6/9) | 63 (10/16) | 64 (16/25) |
≥4 g/dL | 17 (1/6) | 83 (5/6) | 50 (6/12) |
IgM=immunoglobin M. TGA=Treatment Group A. TGB=Treatment Group B.