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. Author manuscript; available in PMC: 2017 Jun 26.
Published in final edited form as: Mod Pathol. 2016 Jan 15;29(3):249–258. doi: 10.1038/modpathol.2015.158

Table 1.

Clinicopathologic Characteristics of Ductal Carcinoma in situ Cases.

DCIS (all cases) Phenotype1

Luminal A Luminal B HER-2 Triple negative

Total Number n=27 16 (62%) 4 (15%) 3 (12%) 3 (12%)

Age (years)
median (range) 38 (18–74) 45 37 33 37
<=40 19 (70%) 10 (62%) 4 (100%) 2 (67%) 2 (67%)
>40 8 (30%) 6 (38%) 0 1 (33%) 1 (33%)

Race
White 14 (52%) 9 (57%) 2 (50%) 2 (50%) 1 (25%)
Black 7 (26%) 4 (25%) 0 (0%) 0 (0%) 2 (50%)
Asian 2 (7%) 1 (6%) 1 (25%) 0 (0%) 0 (0%)
Hispanic 1 (4%) 1 (6%) 0 (0%) 0 (0%) 0 (0%)
Other 3 (11%) 1 (6%) 1 (25%) 1 (25%) 0 (0%)

Nuclear Grade
1 1 (4%) 1 (6%) 0 (0%) 0 (0%) 0 (0%)
2 14 (52%) 11 (69%) 2 (50%) 0 (0%) 0 (0%)
3 12 (44%) 4 (25%) 2 (50%) 3 (100%) 3 (100%)

Necrosis
no 6 (22%) 5 (31%) 0 (0%) 0 (0%) 0 (0%)
yes 21 (78%) 11 (69%) 4 (100%) 3 (100%) 3 (100%)

Multifocality
no 17 (63%) 11 (69%) 2 (50%) 2 (67%) 2 (67%)
yes 10 (37%) 5 (31%) 2 (50%) 1 (33%) 1 (33%)

Size (cm)
mean 2.4 1.7 4.2 4.8 2.8
<1 7 (26%) 6 (38%) 1 (25%) 0 (0%) 0 (0%)
>1 9 (34%) 7 (44%) 0 (0%) 0 (0%) 1 (33%)
>2 2 (7%) 1 (6%) 0 (0%) 1 (33%) 0 (0%)
>3 2 (7%) 1 (6%) 0 (0%) 0 (0%) 1 (33%)
>4 5 (19%) 1 (6%) 3 (75%) 1 (33%) 0 (0%)
NR 2 (7%) 0 (0%) 0 (0%) 1 (33%) 1 (33%)

Recurrence
no 25 (93%) 16 (100%) 0 (0%) 2 (67%) 2 (67%)
yes 2 (7%) 0 (0%) 0 (0%) 1 (33%) 1 (33%)

Associated Infiltrating Carcinoma
no 24 (89%) 15 (94%) 0 (0%) 0 (0%) 1 (33%)
yes 3 (11%) 1 (6%) 0 (0%) 0 (0%) 2 (67%)

(Abbreviations: cm=centimeter; DCIS=ductal carcinoma in situ; HER-2=human epidermal growth factor 2; n=number; NR=not reported;

1

The phenotype for one case was unable to be determined.