Table 1.
DCIS (all cases) | Phenotype1 | ||||
---|---|---|---|---|---|
| |||||
Luminal A | Luminal B | HER-2 | Triple negative | ||
| |||||
Total Number | n=27 | 16 (62%) | 4 (15%) | 3 (12%) | 3 (12%) |
| |||||
Age (years) | |||||
median (range) | 38 (18–74) | 45 | 37 | 33 | 37 |
<=40 | 19 (70%) | 10 (62%) | 4 (100%) | 2 (67%) | 2 (67%) |
>40 | 8 (30%) | 6 (38%) | 0 | 1 (33%) | 1 (33%) |
| |||||
Race | |||||
White | 14 (52%) | 9 (57%) | 2 (50%) | 2 (50%) | 1 (25%) |
Black | 7 (26%) | 4 (25%) | 0 (0%) | 0 (0%) | 2 (50%) |
Asian | 2 (7%) | 1 (6%) | 1 (25%) | 0 (0%) | 0 (0%) |
Hispanic | 1 (4%) | 1 (6%) | 0 (0%) | 0 (0%) | 0 (0%) |
Other | 3 (11%) | 1 (6%) | 1 (25%) | 1 (25%) | 0 (0%) |
| |||||
Nuclear Grade | |||||
1 | 1 (4%) | 1 (6%) | 0 (0%) | 0 (0%) | 0 (0%) |
2 | 14 (52%) | 11 (69%) | 2 (50%) | 0 (0%) | 0 (0%) |
3 | 12 (44%) | 4 (25%) | 2 (50%) | 3 (100%) | 3 (100%) |
| |||||
Necrosis | |||||
no | 6 (22%) | 5 (31%) | 0 (0%) | 0 (0%) | 0 (0%) |
yes | 21 (78%) | 11 (69%) | 4 (100%) | 3 (100%) | 3 (100%) |
| |||||
Multifocality | |||||
no | 17 (63%) | 11 (69%) | 2 (50%) | 2 (67%) | 2 (67%) |
yes | 10 (37%) | 5 (31%) | 2 (50%) | 1 (33%) | 1 (33%) |
| |||||
Size (cm) | |||||
mean | 2.4 | 1.7 | 4.2 | 4.8 | 2.8 |
<1 | 7 (26%) | 6 (38%) | 1 (25%) | 0 (0%) | 0 (0%) |
>1 | 9 (34%) | 7 (44%) | 0 (0%) | 0 (0%) | 1 (33%) |
>2 | 2 (7%) | 1 (6%) | 0 (0%) | 1 (33%) | 0 (0%) |
>3 | 2 (7%) | 1 (6%) | 0 (0%) | 0 (0%) | 1 (33%) |
>4 | 5 (19%) | 1 (6%) | 3 (75%) | 1 (33%) | 0 (0%) |
NR | 2 (7%) | 0 (0%) | 0 (0%) | 1 (33%) | 1 (33%) |
| |||||
Recurrence | |||||
no | 25 (93%) | 16 (100%) | 0 (0%) | 2 (67%) | 2 (67%) |
yes | 2 (7%) | 0 (0%) | 0 (0%) | 1 (33%) | 1 (33%) |
| |||||
Associated Infiltrating Carcinoma | |||||
no | 24 (89%) | 15 (94%) | 0 (0%) | 0 (0%) | 1 (33%) |
yes | 3 (11%) | 1 (6%) | 0 (0%) | 0 (0%) | 2 (67%) |
(Abbreviations: cm=centimeter; DCIS=ductal carcinoma in situ; HER-2=human epidermal growth factor 2; n=number; NR=not reported;
The phenotype for one case was unable to be determined.