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. 2017 May 31;6:e26652. doi: 10.7554/eLife.26652

Figure 6. Shape of behavioral decline changes continuously with lifespan across individuals and strains.

(a) Change in decline rate (pixels/life fraction) versus lifespan for individual N2 animals. (b) Same data as in panel (a) presented for daf-16 mutants. (c) Same data as in panel (a) presented for daf-2 mutants. (d) Change in decline rate (pixels/life fraction) in lowest (white) to highest (dark gray) survivor quartiles. *, p<0.05; **, p<0.01; ***, p<0.001. (e) Change in decline rate (pixels/life fraction) versus lifespan for multiple strains. (f) Mean decline rate change (pixels/life fraction) plotted against mean lifespan for each strain tested. Correlation coefficient r = −0.94, p=0.0006. (g) Standard deviation of decline rate change (pixels/life fraction) plotted against mean lifespan for each strain tested. Correlation coefficient r = −0.70, p=0.055.

DOI: http://dx.doi.org/10.7554/eLife.26652.020

Figure 6.

Figure 6—figure supplement 1. Change in decline rate versus lifespan in individual animals.

Figure 6—figure supplement 1.

(a) Change in decline rate versus lifespan for individuals of all strains tested. (b) Change in decline rate versus lifespan for individual age-1 mutants. (c) Same data as in panel (b) presented for tax-4 mutants. (d) Same data as in panel (b) presented for unc-31 mutants. (e) Same data as in panel (b) presented for lite-1 mutants. (f) Same data as in panel (b) presented for aak-2 mutants.