Table 3. Mean Z-Scores for Composite Cognitive Primary Outcome* by Treatment Group and Week.
| Galantamine | Oxytocin | Placebo | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Week | N | Mean | S.D. | N | Mean | S.D. | N | Mean | S.D. |
| 0 | 15 | -0.22 | 0.47 | 14 | 0.23 | 0.92 | 16 | 0.21 | 0.83 |
| 6 | 15 | -0.05 | 0.68 | 14 | 0.33 | 1.00 | 15 | 0.18 | 0.69 |
| Change | 15 | 0.17 | 0.44 | 14 | 0.10 | 0.37 | 15 | 0.03 | 0.41 |
*
Composite Cognitive Primary Outcome = mean of z-scores from BACS Symbol Digit T-score, HVLT T-score, and Rapid Visual Information Processing (RVIP) test z-score.
ANCOVA estimate of treatment differences on z-scores at Week 6, adjusted for baseline values of the corresponding z-score:
- Galantamine versus placebo: 0.11 ± 0.15; t= 0.71, df=40, p=0.48
- Oxytocin versus placebo: 0.08 ± 0.15 ; t= 0.50, df=40, p=0.62