Table 1.
Maternal and infant characteristics
| Characteristic | Prophylactic Indomethacin N = 2,587 |
No Prophylactic Indomethacin N = 5,244 |
P-value |
|---|---|---|---|
| Maternal | |||
| Gestational hypertension, n (%) | 741 (28.6) | 1346 (25.7) | 0.005 |
| Rupture of membranes > 18 hr, n (%) | 602 (23.3) | 1437 (27.4) | <0.001 |
| Antenatal antibiotics, n (%) | 1805 (69.8) | 3525 (67.2) | 0.02 |
| Antenatal corticosteroids, n (%) | 2377 (91.9) | 4645 (88.6) | <0.001 |
| Cesarean section, n (%) | 1740 (67.3) | 3485 (66.5) | 0.48 |
| Infant | |||
| Gestational age, wk - mean (SD) | 25.9 (1.5) | 26.7 (1.6) | <0.001 |
| Birth weight, g – mean (SD) | 777 (197) | 913 (246) | <0.001 |
| Male, n (%) | 1270 (49.1) | 2744 (52.3) | 0.007 |
| Birth weight < 10th percentile, n (%) | 276 (10.7) | 362 (6.9) | <0.001 |
| Delivery room intubation or CPR, n (%) | 1918 (74.1) | 3465 (66.1) | <0.001 |
| Intubated at 24 hr of life, n (%) | 1721 (66.5) | 2969 (56.6) | <0.001 |
CPR, cardiopulmonary resuscitation (includes chest compressions or treatment with epinephrine); SD, standard deviation