FIG. 1.
Prediction of membrane helices in gH sequences. (A) The two α-helices predicted in HSV-1 gH ectodomain by means of ENSEMBLE (24). Numbers in brackets indicate the first and last residue of the predicted helix. The reliability index (Rel.Index) evaluates the probability of correct prediction on a scale from 0 to 9. (B) Prediction of positionally conserved membrane α-helices in the gH of a number of herpesviruses. Numbers in brackets are as described for panel A. HHV, human herpesvirus; EBV, Epstein-Barr virus; GHV, gallid herpesvirus; EHV, equine herpesvirus; MCMV, murine cytomegalovirus; SHV, suid herpesvirus.