FIG. 1.

Viral suppression in peripheral and mucosal compartments of SIV-infected macaques receiving ART. (A) Plasma compartment. Plasma viral loads were determined at 2, 6, 10, 16, and 26 weeks post-SIV infection in PMPA-treated (closed circles) and untreated (open circles) animals by real-time PCR. P values were calculated by using Student's t test. (B) GALT. Viral loads in GALT were determined at 26 weeks p.i. by real-time PCR. Relative fold changes were calculated by comparison of SIV RNA levels to the lowest level of SIV RNA measured in the PMPA-treated SIV-infected macaques.