Table 3.
OVA-specific IgE titer and allergic rhinitis-like symptms (sneezes and scratches).
Control | Maternal LPS | Allergy(−) | |
---|---|---|---|
OVA specific IgE (OD) | 0.036 ± 0.010 # | 0.026 ± 0.008 # | 0.000 ± 0.000 |
Sneezes and scratches (times/5 min) | 51.4 ± 12.1 ✝ | 60 ± 12.2 # | 28 ± 2.96 |
OVA-specific IgE antibody titer in sera was determined by enzyme-linked immunosorbent assay (ELISA) using OVA to coat plates. Data are shown as values obtained by subtracting optimal density (OD) of non-coated well from OD of OVA-coated well. Allergy(−), female offspring without intranasal challenge with OVA. Allergic rhinitis-like symptoms were evaluated at the number of sneezes and scratches for 5 min under blinded conditions just after the last intranasal instillation with OVA. #:P < 0.05 vs allergy(−), ✝:P < 0.1 vs allergy(−), OVA, ovalbmin; OD, optical density.