Table 1.
Clinical characteristics of muscle stem cell donors.
| Healthy (n = 8) | T2DM (n = 8) | |
|---|---|---|
| Age (years) | 58.0 (50–67) | 58.9 (51–65) |
| BMI (kg/m2) | 25.4 ± 1.8 | 26.2 ± 2.8 |
| Fasting glucose (mmol/L) | 5.6 ± 0.6 | 11.3 ± 4.4** |
| OGTT 2-hour glucose (mmol/L) | 5.1 ± 1.8 | 20.2 ± 3.8**** |
| Fasting insulin (pmol/L) | 29.9 ± 16.5 | 42.3 ± 17.0 |
| OGTT 2-hour insulin (pmol/L) | 154. ± 125.9 | 152.6 ± 46.1 |
| HOMA-IR | 1.2 ± 0.7 | 3.9 ± 3.1* |
| VO2 max (L/min) | 3.0 ± 0.6 | 2.3 ± 0.8 |
| VO2 max (mL/kg/min) | 35.7 ± 8.4 | 26.2 ± 8.4* |
Data are means ± SE. BMI = body mass index; OGTT = oral glucose tolerance test. Glucose values are mmol/L, insulin values are pmol/L. Differences between groups was compared using student's unpaired t-test. *P < 0.05, **P < 0.001, ****P < 0.0001.