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. 2017 May 10;6(7):715–724. doi: 10.1016/j.molmet.2017.05.004

Figure 1.

Figure 1

Effect of ADAMTS5 deficiency on body weight and adipose tissue depots. (A–D) Total body weight (A) and isolated SC AT (B), GON AT (C) and interscapular BAT mass (D) of Adamts5+/+ (white bars; +/+) and Adamts5−/− (black bars; -/-) mice at 8 weeks of age (start) and after 15 weeks on SFD or HFD. (D insert) Macroscopic view of isolated interscapular BAT. (E) H&E staining of BAT of Adamts5+/+ and Adamts5−/− mice kept on HFD. The scale bar represents 100 μm. (F) BAT triglyceride (TG) content of mice kept on SFD or HFD (n = 6). Data are means ± SEM of n determinations. *p < 0.05, **p < 0.01 and ***p < 0.001 versus wild-type on the corresponding diet. #p < 0.01 versus SFD.