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. 2017 May 10;6(7):715–724. doi: 10.1016/j.molmet.2017.05.004

Figure 3.

Figure 3

Effect of ADAMTS5 deficiency on browning of SC WAT. (A) Gene expression profile of “brown” markers in SC adipose tissue of Adamts5+/+ and Adamts5−/− mice kept on SFD or HFD for 15 weeks. mRNA levels are expressed relative to wild-type mice on SFD and normalized for the housekeeping gene β-actin. Data are means ± SEM of 7–10 determinations. (B) Western blotting for UCP-1 is shown on protein extracts of SC AT of Adamts5+/+ (+/+) and Adamts5−/− (-/-) mice kept on SFD or HFD. *p < 0.05, **p < 0.01, ***p < 0.001 versus wild-type; #p < 0.05, ##p < 0.01, ###p < 0.001 versus SFD.