Glucose homeostasis in control and β-Tfb2m−/−mice. (A) Plasma glucose and (B) insulin concentrations in non-fasted control and β-Tfb1m−/− mice at 18 days of age; control, n = 11 and β-Tfb1m−/−, n = 13. (C) Plasma glucose and (D) insulin concentrations in non-fasted control and β-Tfb1m−/− mice at seven weeks of age; control, n = 7 and β-Tfb1m−/−, n = 6. All data are mean ± s.e.m. Statistical differences were examined by unpaired Student's t-test. *P < 0.05, **P < 0.01 and ****P < 0.0001 versus the corresponding value for control mice.