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miR-200c overexpression upregulates the expression of collagen type I and epidermal growth factor (EGF) via the FOG2/PI3K/Akt pathway. (a, c) miR-200c overexpression significantly upregulated the gene expression of collagen type I and EGF secretion in HSCs. (b, c) 25 μM LY-294002 (a PI3K inhibitor) significantly inhibited the gene expression of collagen type I and EGF secretion in LX2-200c cells. ∗∗ means p < 0.01.
