Table 3.

Annotation of variants with strong linkage disequilibrium with the SNP rs4078756 in HaploRegV4.1.

Chr	Pos (hg19)	LD (r2)	Variant	Ref	Alt	ASN freq	Promoter histone marks	DNAse	Proteins bound	Motifs changed
2	177000616	1.00	rs1348808	T	C	0.23	15 tissues	12 tissues	CTBP2	Ets, LF-A1, NF-E2
2	177001145	1.00	rs76652183	G	T	0.23	19 tissues	18 tissues	5 bound proteins	EBF
2	177001378	1.00	rs3731795	A	G	0.27	19 tissues	7 tissues		CTCF, p300
2	177001962	0.96	rs79025511	C	T	0.23	19 tissues	MUS, MUS		Gcm1
2	177004689	0.92	rs72927149	G	C	0.23	12 tissues	6 tissues		Pax-5
2	177005519	1.00	rs79120932	G	T	0.23	19 tissues	32 tissues	5 bound proteins	4 altered motifs
2	177007102	1.00	rs67435554	G	T	0.23
2	177007527	1.00	rs76363873	A	G	0.23	IPSC			GATA, MZF1::1–4
2	177008484	1.00	rs79440139	T	A	0.23				6 altered motifs

Chr: chromosome, Pos: position, LD: linkage disequilibrium in CHB + JPT population, Ref: reference, Alt: alternative, freq: frequency, MUS: musculus, and IPSC: induced pluripotent stem cell.