Table 1.
Characteristics of included trials evaluating corneal collagen cross-linking.
| Study∗ (year) | Country | Number of treated eyes | Mean age (years) | Mean baseline Kmax (diopters) | Control design | Follow-up (months) |
|---|---|---|---|---|---|---|
| Greenstein [16] (2011) | United States | 49 | Not available | 60.4 | Contralateral eye | 12 |
| O'Brart [17] (2011) | United Kingdom | 22 | 29.6 | 53.9 | Contralateral eye | 18 |
| Wittig-Silva [18] (2014) | Australia | 46 | 25.7 | 52.87 | Different patients | 36 |
| Lang [19] (2015) | Germany | 15 | 29.5 | 47.3 | Different patients | 36 |
| Seyedian [20] (2015) | Iran | 26 | 25.6 | 49.43 | Contralateral eye | 12 |
∗First author.